Immunogen: Synthetic peptide from an internal region of human DcR2 • Host: rabbit • Cross Reactivity: (+) human DcR2 • Application(s): WB

DcR2 Polyclonal Antibody – 1 ea

Brand:
Cayman
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Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor.{6839,6837,6838} Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD.{6891,6883,6871} DcR2 has an extracellular TRAIL-binding domain but lacks an intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuates TRAIL-induced apoptosis.  

 

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SKU: 160755 - 1 ea Category:

Description

Immunogen: Synthetic peptide from an internal region of human DcR2 • Host: rabbit • Cross Reactivity: (+) human DcR2 • Application(s): WB

Synonyms: TRAIL-R4|TRUNDD

Immunogen: human DcR2 precursor amino acids 249-263 (GGPERVHRVLFRRRS){6871,6891,6883}

Formulation: 200 µl of peptide affinity-purified polyclonal antibody

Isotype:

Applications: WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Death|Apoptosis

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