Description
This pan-cytokeratin antibody detects cytokeratin isoforms 4, 5, 6, 8, 10, 13, and 18.{11908} Cytokeratins make up a large family of proteins classifed as intermediate filament polypeptides.{11908,15722} They are subdivided into type I (acidic) and type II (basic/neutral) proteins.{15723} Under normal conditions, these proteins are found in epithelial cells as type I/type II pairs.{11908,15740} These pairs provide cellular support as well as contributing to more dynamic processes. They undergo extensive post translational modifications, such as phosphorylation, and are important for cancer diagnostics.{15740,15721} This antibody recognizes human cytokeratins 4, 5, 6, 8, 10, 13, and 18.{11908} Accordingly the molecular migration is isoform dependent and expected to range from 40 to 70 kDa depending upon the cytokeratin composition of the sample.
Synonyms: pan-Cytokeratin
Immunogen:
Formulation: 100 μg of ammonium sulfate-purified IgG
Isotype: IgG1
Applications: FC, IF, IHC, and WB
Origin: Animal/Mouse
Stability: 365 days
Application|Flow Cytometry||Application|Immunocytochemistry||Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cancer
