Maintaining body cholesterol homeostasis is critical for normal physiological functions and is achieved by a highly regulated balance of de novo synthesis

Cholesterol Uptake Cell-Based Assay Kit – 1 ea

Brand:
Cayman
Storage:
-20

Maintaining body cholesterol homeostasis is critical for normal physiological functions and is achieved by a highly regulated balance of de novo synthesis, dietary cholesterol absorption, biliary clearance, and excretion. However, the mechanisms controlling cholesterol absorption are not well understood. A better understanding of the relationship between cholesterol absorption and synthesis may allow for the development of powerful novel strategies for the prevention and treatment of hypercholesterolemia. Cayman’s Cholesterol Uptake Cell-Based Assay Kit provides a convenient tool for studying cholesterol absorption modulators. The kit employs NBD Cholesterol, a fluorescently tagged cholesterol, as a probe for the detection of cholesterol taken up by cultured cells. U-18666A, a cholesterol intracellular trafficking inhibitor, is included as a positive control.  

 

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SKU: 600440 - 1 ea Category:

Description

Maintaining body cholesterol homeostasis is critical for normal physiological functions and is achieved by a highly regulated balance of de novo synthesis, dietary cholesterol absorption, biliary clearance, and excretion. The mechanisms controlling cholesterol absorption are important to understand for the prevention and treatment of hypercholesterolemia. Cayman’s Cholesterol Uptake Cell-Based Assay Kit provides a convenient tool for studying cholesterol absorption modulators. The kit employs NBD Cholesterol, a fluorescently tagged cholesterol, as a probe for the detection of cholesterol taken up by cultured cells. U-18666A, a cholesterol intracellular trafficking inhibitor, is included as a positive control.

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Application|Flow Cytometry||Product Type|Assay Kits|Cell-Based Assays||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias

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