Antigen: synthetic peptide corresponding to mouse caspase-14 amino acids 2-18 • Host: mouse • Cross Reactivity: (+) human and mouse caspase-14 • Application(s): FC (intracellular) and WB • Caspase-14 has a conserved active site pentapeptide

Caspase-14 Monoclonal Antibody (Clone 70A1426) – 1 ea

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Cayman
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Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis.{18384} The precursor form of all caspases is composed of a prodomain and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation, and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into an a2b2 tetramer to form the active enzyme. Caspase-14 has a conserved active site pentapeptide, QACRG. However, no proteolytic or biological activities have been identified so far. Its high expression in embryonic tissues and limited expression in adult tissues suggests that it may have some role during ontogenesis.  

 

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SKU: 13916 - 1 ea Category:

Description

Antigen: synthetic peptide corresponding to mouse caspase-14 amino acids 2-18 • Host: mouse • Cross Reactivity: (+) human and mouse caspase-14 • Application(s): FC (intracellular) and WB • Caspase-14 has a conserved active site pentapeptide, QACRG. However, no proteolytic or biological activities have been identified so far.

Synonyms:

Immunogen: synthetic peptide corresponding to mouse caspase-14 amino acids 2-18

Formulation: 200 µl antibody solution containing 0.09% sodium azide

Isotype:

Applications: FC (intracellular) and WB

Origin:

Stability: 180 days

Application|Flow Cytometry||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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