Immunogen: Peptide from the C-terminal region of human calponin-1 • Host: Rabbit • Species Reactivity: (+) Human

Calponin-1 (C-Term) Rabbit Monoclonal Antibody – 100 µl

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Cayman
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Calponin-1 is an actin binding protein and a component of smooth muscle cell (SMC) contractile machinery that is encoded by CNN1 in humans.{54434,54435} It is a thin filament-associated protein expressed exclusively in SMCs that interacts with actin to inhibit the movement of actin and myosin, as well as the actin-activated MgATPase activity of phosphorylated myosin.{54436} High levels and low levels of calponin-1 are associated with low and high disease progression risk, respectively, in patients with ductal carcinoma in situ (DCIS).{54437} Downregulation of arterial Cnn1 expression promotes proliferation of vascular SMCs (VSMCs) in a DOCA-salt rat model of hypertension and a pig model of hypertension induced by aortic coarctation.{54435} Cayman’s Calponin-1 (C-Term) Rabbit Monoclonal Antibody can be used for immunocytochemistry (ICC) and Western blot (WB) applications.  

 

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SKU: 32207 - 100 µl Category:

Description

Immunogen: Peptide from the C-terminal region of human calponin-1 • Host: Rabbit • Species Reactivity: (+) Human, mouse • Cross Reactivity: (+) Calponin-1 • Applications: ICC, WB

Synonyms: CaP

Immunogen: Peptide from the C-terminal region of human calponin-1

Formulation: 100 µl of protein A-affinity purified monoclonal antibody

Isotype: IgG

Applications: ICC, WB

Origin:

Stability: 365 days

Application|Immunocytochemistry||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cancer||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Vasculature|Smooth Muscle Cells||Research Area|Cell Biology|Cytoskeleton & Motor Proteins

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