Immunogen: Synthetic peptide from the C-terminal region of human BLT1 • Host: Rabbit • Cross Reactivity: (-) BLT2

BLT1 Receptor Polyclonal Antibody – 500 µl

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Cayman
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The leukotriene B4 receptor 1 (BLT1 receptor), cloned from HL-60 human leukemia cells, has 352 amino acids and seven putative membrane-spanning domains.{4425} The primary structure of the receptor is identical to that of a putative purinoceptor, P2Y7, which binds to micromolar concentrations of ATP.{4424} Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus.{4425} Sheep lung membranes have also been identified as a rich source for receptor isolation and purification.{4640} A second LTB4 receptor, BLT2, has recently been cloned and characterized.{8280,8525,8743} This antibody was made against a peptide from the C-terminus of the BLT1 receptor, which is located on the intracellular side of the plasma membrane. Therefore, when performing studies on whole cells, permeabilization of the cells is required for the antibody to enter the cytosol.  

 

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SKU: 120114 - 500 µl Category:

Description

Immunogen: Synthetic peptide from the C-terminal region of human BLT1 • Host: Rabbit • Cross Reactivity: (-) BLT2, CysLT1, and CysLT2 Receptors 1 • Species Reactivity (+) human, bovine, and mouse BLT1 receptor • Application(s): FC, ICC, IHC, and WB • The human BLT1 receptor is a GPCR that mediates the proinflammatory effects of leukotriene B4 (LTB4). Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus.

Synonyms: BLTR1|Leukotriene B4 Receptor 1|LTB4 Receptor 1

Immunogen: Synthetic peptide from the C-terminal region of human BLT1

Formulation: 500 µl of Peptide affinity-purified antibody

Isotype:

Applications: FC, ICC, IHC, and WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Flow Cytometry||Application|Immunocytochemistry||Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Leukotrienes||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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