Immunogen: Human IgG • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) Human IgG1

γ Heavy Chain (human) Monoclonal Antibody – 100 µg

Brand:
Cayman
Storage:

Immunoglobulin G (IgG) is a member of the immunoglobulin superfamily of glycoproteins that plays a central role in the adaptive immune response.{53881,53882} It is produced by B cells and later secreted by plasma cells and is the most abundant circulating antibody in rabbit serum. IgG consists of two identical heavy chains, also known as γ heavy chains, of approximately 50 kDa each and two identical light chains of approximately 25 kDa each.{53881} The heavy chains are linked together by a single disulfide bond to form an Fc region and also combine with the light chains through additional disulfide bonds to form the Fab region, which mediate receptor and antigen binding, respectively. IgG is produced following IgM class-switching in response to infection and is involved in numerous humoral host defense responses, including antibody-dependent cell-mediated cytotoxicity (ADCC), toxin neutralization, and pathogen opsonization.{53881,55170,53883} γ-Heavy chains are truncated and unable to associate with IgG light chains in patients with the rare disease γ heavy chain disease.{53884} Cayman’s γ Heavy Chain (human) Monoclonal antibody can be used for ELISA, immunocytochemistry (ICC), and immunohistochemistry (IHC) applications. The antibody recognizes γ heavy chain from human samples.  

 

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SKU: 32107 - 100 µg Category:

Description

Immunogen: Human IgG • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) Human IgG1, IgG2, IgG3, IgG4; (-) Human IgM, IgA, IgD, IgE; (-) Goat, mouse, rat IgG • Applications: ELISA, ICC, IHC

Synonyms: IgG Heavy Chain

Immunogen: Human IgG

Formulation: 100 µg of protein A-affinity purified monoclonal antibody

Isotype: IgG

Applications: ELISA, ICC, IHC

Origin:

Stability: 365 days

Application|ELISA||Application|Immunocytochemistry||Application|Immunohistochemistry||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cardiovascular System|Blood|Serum Proteins||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Infectious Disease

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