Immunogen: Synthetic peptide corresponding to the N-terminal region of human α-cardiac actin • Host: Rabbit • Species Reactivity: (+) Human

α-Cardiac Actin (N-Term) Rabbit Monoclonal Antibody – 100 µl

Brand:
Cayman
Storage:

α-Cardiac actin is one of the main actin isoforms found in adult cardiac muscle and the predominant actin in the embryonic heart.{60039,60040} It is a globular protein that forms microfilaments at the Z-disc of sarcomeres and interacts with myosin to perform myofilament, and thus cardiac muscle, contractions.{60041} Knockout of Actc1, the gene encoding α-cardiac actin, is embryonic lethal in approximately half of mice and generally lethal within two weeks of birth for the other 50%.{60039} Mutations in ACTC1 are associated with atrial septal defects, familial hypertrophic cardiomyopathy, and idiopathic dilated cardiomyopathy.{60040,60042} Cayman’s α-Cardiac Actin (N-Term) Rabbit Monoclonal Antibody can be used for immunohistochemistry (IHC) and Western blot (WB) applications.  

 

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SKU: 32211 - 100 µl Category:

Description

Immunogen: Synthetic peptide corresponding to the N-terminal region of human α-cardiac actin • Host: Rabbit • Species Reactivity: (+) Human, mouse • Cross Reactivity: (+) Human and mouse α-cardiac actin • Applications: IHC, WB

Synonyms: ACTC1|Actin|alpha Cardiac Muscle 1

Immunogen: Synthetic peptide corresponding to the N-terminal region of human α-cardiac actin

Formulation: 100 µl of protein A-affinity purified monoclonal antibody

Isotype: IgG

Applications: IHC, WB

Origin:

Stability: 365 days

Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cardiovascular System|Cardiovascular Diseases|Cardiomyopathy||Research Area|Cardiovascular System|Heart|Myocardial Hypertrophy

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