Antibodies
Showing 1501–1650 of 2318 results
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Immunogen: Peroxynitrite-treated keyhole limpet hemocyanin • Host: Mouse • Species Reactivity: Species independent • Cross Reactivity: (+) Chlorotyrosine (weakly) • Applications: ELISA, WB
Brand:CaymanSKU:10006966- 100 µgAvailable on backorder
Immunogen: Peroxynitrite-treated keyhole limpet hemocyanin • Host: Mouse • Species Reactivity: Species independent • Cross Reactivity: (+) Chlorotyrosine (weakly) • Applications: ELISA, WB
Brand:CaymanSKU:10006966- 100 µg
Immunogen: Peroxynitrite-treated keyhole limpet hemocyanin • Host: Rabbit • Species Reactivity: (+) Species independent • Cross Reactivity: None listed • Applications: WB
Brand:CaymanSKU:10189540- 1 ea Immunogen: Peroxynitrite-treated keyhole limpet hemocyanin • Host: Rabbit • Species Reactivity: (+) Species independent • Cross Reactivity: None listed • Applications: WB
Brand:CaymanSKU:10189540- 1 eaAvailable on backorder
Antigen: fusion protein containing amino acids 1-564 of the NR1 subunit of rat NMDA receptor • Host: mouse • Cross Reactivity: (+) rat and mouse NMDA receptor • Application(s): IP and WB • The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ.
Brand:CaymanSKU:10607- 1 ea Antigen: fusion protein containing amino acids 1-564 of the NR1 subunit of rat NMDA receptor • Host: mouse • Cross Reactivity: (+) rat and mouse NMDA receptor • Application(s): IP and WB • The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ.
Brand:CaymanSKU:10607- 1 eaAvailable on backorder
Antigen: fusion protein from the C-terminus of the NR2A subunit of rat NMDA receptor • Host: rabbit • Cross Reactivity: (+) human, mouse, and rat NMDA receptor • Application(s): IHC, IP, and WB • The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. Channels with physiological activity are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.
Brand:CaymanSKU:10608- 1 ea Antigen: fusion protein from the C-terminus of the NR2A subunit of rat NMDA receptor • Host: rabbit • Cross Reactivity: (+) human, mouse, and rat NMDA receptor • Application(s): IHC, IP, and WB • The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. Channels with physiological activity are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.
Brand:CaymanSKU:10608- 1 eaAvailable on backorder
Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Tyr1252 of the human NMDA Receptor NR2B Subunit • Host: rabbit • Cross Reactivity: (+) human and rat NMDA receptor; expected to react with bovine, canine, chicken, mouse, non-human primates, and zebrafish NMDA receptor • Application(s): WB • Phosphorylation of Tyr1252 in NR2B is thought to potentiate NMDA receptor-dependent influx of calcium.
Brand:CaymanSKU:10009759- 1 eaAvailable on backorder
Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Tyr1252 of the human NMDA Receptor NR2B Subunit • Host: rabbit • Cross Reactivity: (+) human and rat NMDA receptor; expected to react with bovine, canine, chicken, mouse, non-human primates, and zebrafish NMDA receptor • Application(s): WB • Phosphorylation of Tyr1252 in NR2B is thought to potentiate NMDA receptor-dependent influx of calcium.
Brand:CaymanSKU:10009759- 1 ea Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Tyr1336 of the human NMDA Receptor NR2B Subunit • Host: rabbit • Cross Reactivity: (+) human and rat NMDA receptor; expected to react with bovine, canine, chicken, mouse, non-human primates, and zebrafish NMDA receptor • Application(s): WB • Phosphorylation of Tyr1336 in NR2B is thought to potentiate NMDA receptor-dependent influx of calcium. Ischemia may also increase the phosphorylation of this site.
Brand:CaymanSKU:10009760- 1 eaAvailable on backorder
Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Tyr1336 of the human NMDA Receptor NR2B Subunit • Host: rabbit • Cross Reactivity: (+) human and rat NMDA receptor; expected to react with bovine, canine, chicken, mouse, non-human primates, and zebrafish NMDA receptor • Application(s): WB • Phosphorylation of Tyr1336 in NR2B is thought to potentiate NMDA receptor-dependent influx of calcium. Ischemia may also increase the phosphorylation of this site.
Brand:CaymanSKU:10009760- 1 ea Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Tyr1472 of NMDA Receptor NR2B Subunit • Host: rabbit • Cross Reactivity: (+) human and rat NMDA receptor; expected to react with bovine, canine, chicken, mouse, non-human primates, and zebrafish NMDA receptor • Application(s): WB • Phosphorylation of Tyr1472 on NR2B may regulate the functional expression of the receptor in LTP and other forms of plasticity.
Brand:CaymanSKU:10009761- 1 eaAvailable on backorder
Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Tyr1472 of NMDA Receptor NR2B Subunit • Host: rabbit • Cross Reactivity: (+) human and rat NMDA receptor; expected to react with bovine, canine, chicken, mouse, non-human primates, and zebrafish NMDA receptor • Application(s): WB • Phosphorylation of Tyr1472 on NR2B may regulate the functional expression of the receptor in LTP and other forms of plasticity.
Brand:CaymanSKU:10009761- 1 ea Antigen: fusion protein from the C-terminus of the NR2B subunit of rat NMDA receptor • Host: rabbit • Cross Reactivity: (+) human, rat, and mouse NMDA receptor • Application(s): IHC, IP, and WB • Overexpression of the NR2B-subunit of the NMDA receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression.
Brand:CaymanSKU:10609- 1 ea Antigen: fusion protein from the C-terminus of the NR2B subunit of rat NMDA receptor • Host: rabbit • Cross Reactivity: (+) human, rat, and mouse NMDA receptor • Application(s): IHC, IP, and WB • Overexpression of the NR2B-subunit of the NMDA receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression.
Brand:CaymanSKU:10609- 1 eaAvailable on backorder
Immunogen: Synthetic peptide from the C-terminal region of human nNOS • Host: Rabbit • Cross Reactivity: (−) eNOS and iNOS • Species Reactivity: (+) Human and rat • Applications: ICC, IHC, and WB
Brand:CaymanSKU:160870- 500 µl Immunogen: Synthetic peptide from the C-terminal region of human nNOS • Host: Rabbit • Cross Reactivity: (−) eNOS and iNOS • Species Reactivity: (+) Human and rat • Applications: ICC, IHC, and WB
Brand:CaymanSKU:160870- 500 µlAvailable on backorder
Immunogen: Recombinant protein fragment from the internal region of human Nod2 • Clone designation: 2D9 · Host: Mouse · Species Reactivity: (+) Human; other species not tested · Application: WB • Nod2 is a member of the apoptosis regulating protein family that has caspase recruitment-domains (CARDs) and also includes Apaf-1 and Nod1. Nod1 and Nod2 act as intracellular receptors for bacterial lipopolysaccharides, activate NF-κB, and contribute to inflammatory bowel disease.
Brand:CaymanSKU:10004942- 1 eaAvailable on backorder
Immunogen: Recombinant protein fragment from the internal region of human Nod2 • Clone designation: 2D9 · Host: Mouse · Species Reactivity: (+) Human; other species not tested · Application: WB • Nod2 is a member of the apoptosis regulating protein family that has caspase recruitment-domains (CARDs) and also includes Apaf-1 and Nod1. Nod1 and Nod2 act as intracellular receptors for bacterial lipopolysaccharides, activate NF-κB, and contribute to inflammatory bowel disease.
Brand:CaymanSKU:10004942- 1 ea
Immunogen: Recombinant protein fragment from the internal region of human Nod2 • Host: Rabbit • Species reactivity: (+) Human • Applications: WB; may not detect basal levels of Nod2 in monocytes
Brand:CaymanSKU:160777- 1 ea Immunogen: Recombinant protein fragment from the internal region of human Nod2 • Host: Rabbit • Species reactivity: (+) Human • Applications: WB; may not detect basal levels of Nod2 in monocytes
Brand:CaymanSKU:160777- 1 eaAvailable on backorder
Immunogen: Synthetic peptide from the C-terminal region of human Nrf2 protein • Host: Rabbit • Species Reactivity: (+) Human, mouse, rat • Cross Reactivity: N/A • Applications: FC, ICC, IF, WB • MW = 90 kDa
Brand:CaymanSKU:10214- 1 ea Immunogen: Synthetic peptide from the C-terminal region of human Nrf2 protein • Host: Rabbit • Species Reactivity: (+) Human, mouse, rat • Cross Reactivity: N/A • Applications: FC, ICC, IF, WB • MW = 90 kDa
Brand:CaymanSKU:10214- 1 eaAvailable on backorder
Immunogen: Peptide from the N-terminal region of human Nrf2 protein • Host: Rabbit • Species Reactivity: (+) Human, mouse, rat • Applications: FC, ICC, IF, WB • MW = 67 and 90 kDa for native and polyubiquitinated Nrf2, respectively
Brand:CaymanSKU:14114- 1 eaAvailable on backorder
Immunogen: Peptide from the N-terminal region of human Nrf2 protein • Host: Rabbit • Species Reactivity: (+) Human, mouse, rat • Applications: FC, ICC, IF, WB • MW = 67 and 90 kDa for native and polyubiquitinated Nrf2, respectively
Brand:CaymanSKU:14114- 1 ea
Immunogen: Recombinant mouse Olig1 • Host: Rabbit • Species Reactivity: (+) Human, Mouse, Rat • Applications: ICC, IHC, IP, WB • MW = ~27 kDa
Brand:CaymanSKU:29287- 100 µl Immunogen: Recombinant mouse Olig1 • Host: Rabbit • Species Reactivity: (+) Human, Mouse, Rat • Applications: ICC, IHC, IP, WB • MW = ~27 kDa
Brand:CaymanSKU:29287- 100 µlAvailable on backorder
Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser10,13,14 of human Olig2 • Host: Rabbit • Species Reactivity: (+) Human, Mouse, Rat • Applications: WB • MW = ~32 kDa
Brand:CaymanSKU:29289- 100 µl Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser10,13,14 of human Olig2 • Host: Rabbit • Species Reactivity: (+) Human, Mouse, Rat • Applications: WB • MW = ~32 kDa
Brand:CaymanSKU:29289- 100 µlAvailable on backorder
Immunogen: Recombinant mouse Olig2 • Host: Rabbit • Species Reactivity: (+) Human, mouse, rat • Applications: ICC, IHC, IP, WB • MW = ~32 kDa
Brand:CaymanSKU:29288- 100 µl Immunogen: Recombinant mouse Olig2 • Host: Rabbit • Species Reactivity: (+) Human, mouse, rat • Applications: ICC, IHC, IP, WB • MW = ~32 kDa
Brand:CaymanSKU:29288- 100 µlAvailable on backorder
Immunogen: Peptide from C-Terminal region of human optineurin protein • Host: Mouse • Species Reactivity: (+) Human • Applications: Immunocytochemistry • MW = 66 kDa
Brand:CaymanSKU:27230- 100 µgAvailable on backorder
Immunogen: Peptide from C-Terminal region of human optineurin protein • Host: Mouse • Species Reactivity: (+) Human • Applications: Immunocytochemistry • MW = 66 kDa
Brand:CaymanSKU:27230- 100 µg
Immunogen: synthetic peptide from C-terminal region of human optineurin • Host: rabbit • Species-Reactivity: (+) human optineurin • Applications: IHC and WB
Brand:CaymanSKU:100000- 1 ea Immunogen: synthetic peptide from C-terminal region of human optineurin • Host: rabbit • Species-Reactivity: (+) human optineurin • Applications: IHC and WB
Brand:CaymanSKU:100000- 1 eaAvailable on backorder
Immunogen: Synthetic peptide from the internal region of human optineurin • Host: rabbit • Species Reactivity: (+) Human; (−) Murine, rat, and porcine • Applications: IHC and WB
Brand:CaymanSKU:100002- 500 µl Immunogen: Synthetic peptide from the internal region of human optineurin • Host: rabbit • Species Reactivity: (+) Human; (−) Murine, rat, and porcine • Applications: IHC and WB
Brand:CaymanSKU:100002- 500 µlAvailable on backorder
Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Thr180 and phospho-Tyr182 of rat p38 MAPK • Host: rabbit • Cross Reactivity: (+) human p38 MAPK • Application(s): WB • p38 MAPK is activated by both inflammatory cytokines and by stress. It is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system. Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.
Brand:CaymanSKU:10009177- 1 eaAvailable on backorder
Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Thr180 and phospho-Tyr182 of rat p38 MAPK • Host: rabbit • Cross Reactivity: (+) human p38 MAPK • Application(s): WB • p38 MAPK is activated by both inflammatory cytokines and by stress. It is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system. Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.
Brand:CaymanSKU:10009177- 1 ea
Antigen: human full length p38 MAPK • Host: mouse, clone 9F12 • Cross Reactivity: (+) human, mouse, and rat p38 MAPK • Application(s): FC, ICC, and WB • p38 MAPK is a member of the serine-threonine MAPK family that triggers many cellular processes including cell cycle, development, and apoptosis.
Brand:CaymanSKU:10011301- 1 ea Antigen: human full length p38 MAPK • Host: mouse, clone 9F12 • Cross Reactivity: (+) human, mouse, and rat p38 MAPK • Application(s): FC, ICC, and WB • p38 MAPK is a member of the serine-threonine MAPK family that triggers many cellular processes including cell cycle, development, and apoptosis.
Brand:CaymanSKU:10011301- 1 eaAvailable on backorder
Immunogen: Peptide corresponding to human p38α MAPK (phospho-Thr180/Tyr182) • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) p38α MAPK (phospho-Thr180/Tyr182); (-) Unmodified p38α MAPK, p38α MAPK (phospho-Thr180), p38α MAPK (phospho-Tyr182) • Applications: IHC, WB • MW: ~38 kDa
Brand:CaymanSKU:32197- 100 µlAvailable on backorder
Immunogen: Peptide corresponding to human p38α MAPK (phospho-Thr180/Tyr182) • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) p38α MAPK (phospho-Thr180/Tyr182); (-) Unmodified p38α MAPK, p38α MAPK (phospho-Thr180), p38α MAPK (phospho-Tyr182) • Applications: IHC, WB • MW: ~38 kDa
Brand:CaymanSKU:32197- 100 µl
Immunogen: Peptide corresponding to p38α MAPK (300-360) • Host: Rabbit • Species Reactivity: (+) Human • Applications: IHC, WB • MW: ~38 kDa
Brand:CaymanSKU:32199- 100 µlAvailable on backorder
Immunogen: Peptide corresponding to p38α MAPK (300-360) • Host: Rabbit • Species Reactivity: (+) Human • Applications: IHC, WB • MW: ~38 kDa
Brand:CaymanSKU:32199- 100 µl Antigen: amino acids around phospho-Ser392 • Host: rabbit • Application(s): WB • Nearly 50% of human tumors have mutated or non-functional p53. p53 amino acid residues can be modified by phosphorylation and acetylation. In vivo phosphorylation of p53 residues alters signal transduction events that warrant further investigation.
Brand:CaymanSKU:10004807- 1 eaAvailable on backorder
Antigen: amino acids around phospho-Ser392 • Host: rabbit • Application(s): WB • Nearly 50% of human tumors have mutated or non-functional p53. p53 amino acid residues can be modified by phosphorylation and acetylation. In vivo phosphorylation of p53 residues alters signal transduction events that warrant further investigation.
Brand:CaymanSKU:10004807- 1 ea
Epitope: Binds to N-terminal amino acids 16-25 of wild-type and mutant p53 • Host: Mouse • Clone: BP53-12 • Isotype: IgG2a • Species Reactivity: (+) Human and mouse; other species not tested • Applications: FC, IHC (paraffin-embedded tissue), IP, and WB • Cellular p53, often called the ‘guardian of the genome,’ is a transcription factor that is activated in response to cellular stress (DNA damage, hypoxia, heat shock, etc.) and acts to prevent further proliferation of the stressed cell by induction of cell cycle arrest or apoptotic mediators.
Brand:CaymanSKU:10004806- 1 eaAvailable on backorder
Epitope: Binds to N-terminal amino acids 16-25 of wild-type and mutant p53 • Host: Mouse • Clone: BP53-12 • Isotype: IgG2a • Species Reactivity: (+) Human and mouse; other species not tested • Applications: FC, IHC (paraffin-embedded tissue), IP, and WB • Cellular p53, often called the ‘guardian of the genome,’ is a transcription factor that is activated in response to cellular stress (DNA damage, hypoxia, heat shock, etc.) and acts to prevent further proliferation of the stressed cell by induction of cell cycle arrest or apoptotic mediators.
Brand:CaymanSKU:10004806- 1 ea
Immunogen: A synthetic peptide from the C-terminal region of human p62 • Host: Rabbit • Species Reactivity: (+) Human • Applications: ELISA and WB
Brand:CaymanSKU:24693- 500 µlAvailable on backorder
Immunogen: A synthetic peptide from the C-terminal region of human p62 • Host: Rabbit • Species Reactivity: (+) Human • Applications: ELISA and WB
Brand:CaymanSKU:24693- 500 µl
Immunogen: Recombinant human PAD1 protein • Clone designation: 6B4 • Host: Mouse • Cross Reactivity: (-) PAD2, PAD3, and PAD4 • Species Reactivity: (+) Human • Isotype: IgG2b • Applications: ELISA and WB
Brand:CaymanSKU:22997- 100 µgAvailable on backorder
Immunogen: Recombinant human PAD1 protein • Clone designation: 6B4 • Host: Mouse • Cross Reactivity: (-) PAD2, PAD3, and PAD4 • Species Reactivity: (+) Human • Isotype: IgG2b • Applications: ELISA and WB
Brand:CaymanSKU:22997- 100 µg
Immunogen: Full length recombinant human PAD2 protein • Clone: 9F7 • Host: Mouse • Isotype: IgG1 Species Reactivity: (+) Human • Applications: ELISA, IHC, and WB
Brand:CaymanSKU:19822- 100 µgAvailable on backorder
Immunogen: Full length recombinant human PAD2 protein • Clone: 9F7 • Host: Mouse • Isotype: IgG1 Species Reactivity: (+) Human • Applications: ELISA, IHC, and WB
Brand:CaymanSKU:19822- 100 µg
Immunogen: Full length recombinant PAD3 protein • Clone designation: 4E5 • Host: Mouse • Cross reactivity: (+) PAD3; (-) PAD1, PAD2, PAD4 • Species Reactivity: (+) Human • Isotype: IgG1 • Applications: ELISA and WB,
Brand:CaymanSKU:24377- 100 µgAvailable on backorder
Immunogen: Full length recombinant PAD3 protein • Clone designation: 4E5 • Host: Mouse • Cross reactivity: (+) PAD3; (-) PAD1, PAD2, PAD4 • Species Reactivity: (+) Human • Isotype: IgG1 • Applications: ELISA and WB,
Brand:CaymanSKU:24377- 100 µg
Immunogen: Full length recombinant PAD4 protein • Clone: 11F9 • Host: Mouse • Isotype: IgG1 Species Reactivity: (+) Human • Applications: ELISA, WB
Brand:CaymanSKU:19671- 100 µgAvailable on backorder
Immunogen: Full length recombinant PAD4 protein • Clone: 11F9 • Host: Mouse • Isotype: IgG1 Species Reactivity: (+) Human • Applications: ELISA, WB
Brand:CaymanSKU:19671- 100 µg
Immunogen: Full length recombinant PAD4 protein • Clone: 6D8 • Host: Mouse • Isotype: IgG1 • Species Reactivity: (+) Human • Applications: ELISA, WB
Brand:CaymanSKU:19669- 100 µgAvailable on backorder
Immunogen: Full length recombinant PAD4 protein • Clone: 6D8 • Host: Mouse • Isotype: IgG1 • Species Reactivity: (+) Human • Applications: ELISA, WB
Brand:CaymanSKU:19669- 100 µg
Immunogen: Full-length recombinant PAD6 protein • Host: Mouse • Cross reactivity: (-) PAD1, PAD2, PAD3, PAD4 • Species Reactivity: (+) Human PAD6 • Isotype: IgG1 • Applications: ELISA and WB • MW = ~77 kDa
Brand:CaymanSKU:25965- 100 µgAvailable on backorder
Immunogen: Full-length recombinant PAD6 protein • Host: Mouse • Cross reactivity: (-) PAD1, PAD2, PAD3, PAD4 • Species Reactivity: (+) Human PAD6 • Isotype: IgG1 • Applications: ELISA and WB • MW = ~77 kDa
Brand:CaymanSKU:25965- 100 µg
Immunogen: Synthetic peptide from the C-terminal region of human PAF-AH • Host: Rabbit • Species Reactivity: (+) Human; (−) Mouse • Application(s): IHC and WB
Brand:CaymanSKU:160603- 500 µl Immunogen: Synthetic peptide from the C-terminal region of human PAF-AH • Host: Rabbit • Species Reactivity: (+) Human; (−) Mouse • Application(s): IHC and WB
Brand:CaymanSKU:160603- 500 µlAvailable on backorder
Immunogen: Synthetic peptide from the internal region of human PAF receptor • Host: Mouse, 11A4 clone 21 • Species Reactivity: (+) Human, bovine, and porcine PAF receptor • Isotype: IgG2a • Application(s): ELISA, FC, and ICC; does not work for WB • PAF is a biologically active phospholipid whose biological effects include activation of platelets, polymorphonuclear leukocytes, monocytes, and macrophages. PAF increases vascular permeability, decreases cardiac output, induces hypotension, and stimulates uterine contraction.
Brand:CaymanSKU:160600- 1 ea Immunogen: Synthetic peptide from the internal region of human PAF receptor • Host: Mouse, 11A4 clone 21 • Species Reactivity: (+) Human, bovine, and porcine PAF receptor • Isotype: IgG2a • Application(s): ELISA, FC, and ICC; does not work for WB • PAF is a biologically active phospholipid whose biological effects include activation of platelets, polymorphonuclear leukocytes, monocytes, and macrophages. PAF increases vascular permeability, decreases cardiac output, induces hypotension, and stimulates uterine contraction.
Brand:CaymanSKU:160600- 1 eaAvailable on backorder
Immunogen: synthetic peptide from the N-terminal region of human protein PAF receptor • Host: rabbit • Species Reactivity: (+) Human and green monkey PAF receptor • Application(s): FC, IHC, and WB • PAF is a biologically active phospholipid whose biological effects include activation of platelets, polymorphonuclear leukocytes, monocytes, and macrophages. PAF increases vascular permeability, decreases cardiac output, induces hypotension, and stimulates uterine contraction.
Brand:CaymanSKU:160602- 1 ea Immunogen: synthetic peptide from the N-terminal region of human protein PAF receptor • Host: rabbit • Species Reactivity: (+) Human and green monkey PAF receptor • Application(s): FC, IHC, and WB • PAF is a biologically active phospholipid whose biological effects include activation of platelets, polymorphonuclear leukocytes, monocytes, and macrophages. PAF increases vascular permeability, decreases cardiac output, induces hypotension, and stimulates uterine contraction.
Brand:CaymanSKU:160602- 1 eaAvailable on backorder
Antigen: synthetic peptide containing amino acids near the 214/215 cleavage site of human PARP • Isotype: IgG2bκ • Host: mouse • Cross Reactivity: (+) human PARP • Application(s): FC (intracellular) and WB • PARP is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24 kDa fragment containing the DNA binding domain and an 89 kDa fragment containing the catalytic and automodification domains. The 24 kDa fragment irreversibly binds to DNA and may contribute to the irreversibility of apoptosis by blocking the access of DNA repair enzymes to DNA strand breaks.
Brand:CaymanSKU:13557- 1 eaAvailable on backorder
Antigen: synthetic peptide containing amino acids near the 214/215 cleavage site of human PARP • Isotype: IgG2bκ • Host: mouse • Cross Reactivity: (+) human PARP • Application(s): FC (intracellular) and WB • PARP is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24 kDa fragment containing the DNA binding domain and an 89 kDa fragment containing the catalytic and automodification domains. The 24 kDa fragment irreversibly binds to DNA and may contribute to the irreversibility of apoptosis by blocking the access of DNA repair enzymes to DNA strand breaks.
Brand:CaymanSKU:13557- 1 ea
Immunogen: Peptide from the N-terminal region of human paxillinα/β/γ • Host: Rabbit • Species Reactivity: (+) Human • Applications: ICC, WB
Brand:CaymanSKU:32209- 100 µlAvailable on backorder
Immunogen: Peptide from the N-terminal region of human paxillinα/β/γ • Host: Rabbit • Species Reactivity: (+) Human • Applications: ICC, WB
Brand:CaymanSKU:32209- 100 µl Host: Mouse, clone IPO-38 • Cross Reactivity: (+) Multiple species (species- and tissue-unspecific) • Application(s): FC, ICC, IHC (frozen and paraffin-embedded sections), and WB
Brand:CaymanSKU:10004805- 1 eaAvailable on backorder
Host: Mouse, clone IPO-38 • Cross Reactivity: (+) Multiple species (species- and tissue-unspecific) • Application(s): FC, ICC, IHC (frozen and paraffin-embedded sections), and WB
Brand:CaymanSKU:10004805- 1 ea
Immunogen: Purified human recombinant PCSK9 • Host: Mouse • Clone: 15A6 • Isotype: IgG1 • Species Reactivity: (+) Human recombinant PCSK9 • Application: WB
Brand:CaymanSKU:10218- 1 ea Immunogen: Purified human recombinant PCSK9 • Host: Mouse • Clone: 15A6 • Isotype: IgG1 • Species Reactivity: (+) Human recombinant PCSK9 • Application: WB
Brand:CaymanSKU:10218- 1 eaAvailable on backorder
Immunogen: Purified recombinant human PCSK9 • Host: Rabbit· Species Reactivity: (+) Human, mouse, and rat • Application: WB
Brand:CaymanSKU:10240- 1 ea Immunogen: Purified recombinant human PCSK9 • Host: Rabbit· Species Reactivity: (+) Human, mouse, and rat • Application: WB
Brand:CaymanSKU:10240- 1 eaAvailable on backorder
Immunogen: Synthetic peptide from an internal region of human PCSK9 • Host: Rabbit • Species Reactivity: (+) Human, mouse, and rat • Applications: IF and WB • PCSK9 is a member of the subtilisin serine protease family with an important role in lipoprotein metabolism. Several gain of function mutations in the PCSK9 gene are associated with hypercholesterolemia which is characterized by an increase in LDL cholesterol levels.
Brand:CaymanSKU:10007185- 500 μlAvailable on backorder