Immunogen: Peptide from the internal region of human S1P1 • Host: Rabbit • Species Reactivity: (+) Human S1P1

S1P1 Polyclonal Antibody (protein A-purified) – 1 ea

Brand:
Cayman
Storage:

Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8.{11895,12477} S1P1 primarily couples with pertussis toxin-sensitive Gi/o proteins to mediate S1P-induced cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.{11895,12477,10628} Expression of S1P1 is abundant in embryological vasculature and is ubiquitously expressed in adult cells, suggesting diverse physiological functions of this receptor.{12477} The human and mouse S1P1 receptors have 382 amino acids with an estimated molecular weight of 43 kDa. Glycosylation at the N-terminal extracellular domain may cause the protein to migrate at a higher position in SDS-PAGE.{12476} Cayman’s S1P1 Polyclonal Antibody (protein A-purified) can be used for western blot applications. The antibody recognizes S1P1 at 42 kDa from human, mouse, porcine, and rat samples.  

 

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SKU: 20208 - 1 ea Category:

Description

Immunogen: Peptide from the internal region of human S1P1 • Host: Rabbit • Species Reactivity: (+) Human S1P1, Mouse S1P1, Porcine S1P1 Rat S1P1 • Application(s): WB

Synonyms: EDG-1|S1PR1|Sphingosine-1-phosphate Receptor 1

Immunogen: Peptide from the internal region of human S1P1

Formulation: 500 µl of protein-A purified IgG

Isotype:

Applications: WB

Origin:

Stability: 365 days

Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cytoskeleton & Motor Proteins

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