Immunogen: Recombinant human renin protein • Clone designation: 3G10 • Host: Mouse • Species Reactivity: (+) Human • Isotype: IgG2b • Application: (+) IP; (-) WB

Renin Monoclonal Antibody (Clone 3G10) – 200 µg

Brand:
Cayman
Storage:

Cayman’s Renin Monoclonal Antibody (Clone 3G10) is directed against the full length renin (human recombinant) protein (Item No. 10006217). Renin is an aspartyl protease of approximately 40 kDa produced in the kidney by juxtaglomerular cells of the macula densa.{12331} Renin converts angiotensinogen into angiotensin I, activating a major arm of renal sodium and volume auto-regulation. Native human renin is a glycoprotein derived from preprorenin by sequential cleavage. The first cleavage releases the signal peptide (amino acids 1-23), forming the prorenin (44 kDa). The second cleavage removes the propeptide (amino acids 24-66), forming the functional renin protein (40 kDa). This antibody detects both the active renin and prorenin.  

 

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SKU: 17624 - 200 µg Category:

Description

Immunogen: Recombinant human renin protein • Clone designation: 3G10 • Host: Mouse • Species Reactivity: (+) Human • Isotype: IgG2b • Application: (+) IP; (-) WB

Synonyms:

Immunogen: Recombinant human renin protein

Formulation: 100 µl caprylic acid/ammonium sulfate-purified monoclonal antibody

Isotype: IgG2b

Applications: (+) IP; (-) WB

Origin:

Stability: 365 days

Application|Immunoprecipitation||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Kidney & Renal Disease||Research Area|Endocrinology & Metabolism|Hormones & Receptors

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