Immunogen: Synthetic peptide from the internal region of human FFAR4 (GPR120) • Host: Rabbit • Species Reactivity: (+) Human • Application(s): ELISA and WB

FFAR4 (GPR120) (Internal) Polyclonal Antibody – 1 ea

Brand:
Cayman
Storage:

GPR120 is a G protein-coupled receptor (GPR) expressed in adipocytes and pro-inflammatory macrophages that is activated by long chain free fatty acids.{13205} The activation of GPR120 results in elevated calcium ions and activation of the ERK cascade.{13205} ω-3 Fatty acids, such as docosahexaenoic acid and eicosapentaenoic acid initiate GPR120 signaling resulting in inhibition of lipopolysaccharide and TNF-α inflammatory signaling pathways in a β-arrestin2/TAB1 dependant manner.{22326} The anti-inflammatory effects of GPR120 are indirectly involved with promoting insulin secretion.{13205} GPR120 also mediates free fatty acid induced apoptosis inhibition in the enteroendocrin cell line STC-1.{13205} Cayman’s internal polyclonal antibody detects GPR120 in LoVo and PC3 cell lysates. The predicted size for GPR120 is 42.2 kDa and the observed size is approximately 40 kDa by western blot.  

 

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SKU: 14904 - 1 ea Category:

Description

Immunogen: Synthetic peptide from the internal region of human FFAR4 (GPR120) • Host: Rabbit • Species Reactivity: (+) Human • Application(s): ELISA and WB

Synonyms: Free Fatty Acid Receptor 4|G Protein-Coupled Receptor 120|GPR120|GPR129|O3FAR1|PGR4

Immunogen: Synthetic peptide from the internal region of human FFAR4 (GPR120)

Formulation: 500 μl of peptide affinity-purified antibody

Isotype:

Applications: ELISA and WB

Origin:

Stability: 365 days

Application|ELISA||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Cell Signaling|ERK/MAPK Signaling||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Immunology & Inflammation|Innate Immunity|Pattern Recognition

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