Antigen: human full length A2AR; the antibody recognizes amino acids 213-220 as determined by epitope mapping • Host: mouse

Adenosine Receptor A2A Monoclonal Antibody (Clone 7FG-G5-A2) – 1 ea

Brand:
Cayman
Storage:

Adenosine receptor A2A Monoclonal Antibody (A2AR) is a multi-pass membrane protein that is normally localized to the plasma membrane.{15465} This receptor is part of the G protein-coupled receptor family that binds adenosine and serves multiple functions. Antagonists of this receptor have been targeted for the treatment of Parkinson’s disease.{15466,5049} Early reports found this receptor is found primarily in the brain striatum, but is also found in immune cells and other tissues as well.{15466} A2AR is comprised of 412 amino acids with an expected molecular weight of 45 kDa.{16148,15465} However multiple glycosylation sites exist that may explain the retarded migration observed by western blotting (45-50 kDa).{15465} This antibody has been extensively characterized and the epitope has been mapped to the third intracellular loop of the receptor.{16545}  

 

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SKU: 10011454 - 1 ea Category:

Description

Antigen: human full length A2AR; the antibody recognizes amino acids 213-220 as determined by epitope mapping • Host: mouse, clone 7FG-G5-A2 • Cross Reactivity: (+) human A2AR • Application(s): WB • A2AR is a multi-pass membrane protein found primarily in the brain striatum, but also in immune cells and other tissues and may play a role in the treatment of Parkinson’s disease

Synonyms: A2AR|ADORA2A

Immunogen: human full length A2AR; the antibody recognizes amino acids 213-220 (SQPLPGER) as determined by epitope mapping

Formulation: 500 µg affinity-purified IgG2a in 500 µl PBS, pH 7.2, containing 50% glycerol, 0.5 mg/ml BSA, and 0.02% sodium azide

Isotype:

Applications: WB

Origin: Animal/Mouse

Stability: 365 days

Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease

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