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Bim/BOD (IN) Polyclonal Antibody – 25 µg

Brand:
Cayman
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Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bim/BOD is a group of three splice variants, BimEL, BimL and BimS, with apparent molecular masses of ~23, 16, and 13 kDa, respectively. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse, and rat.{7144,7141} Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.{7144,7141}  

 

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SKU: 10011385 - 25 µg Category:

Description

Antigen: internal central human Bim amino acids · Host: rabbit · Cross Reactivity: (+) human, mouse, and rat Bim/BOD (IN) · Applications: IHC and WB • Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, -xL, and -w and induces apoptosis.

Synonyms:

Immunogen: internal central human Bim amino acids

Formulation: Immunoaffinity chromatography purified IgG at 1 mg/ml in PBS containing 0.02% sodium azide

Isotype:

Applications: WB and IHC

Origin: Animal/Rabbit

Stability: 365 days

Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Death|Apoptosis

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