Antigen: human SPHK 1 amino acids 264-274 • Host: rabbit • Cross Reactivity: (+) human and mouse SPHK 1

Sphingosine Kinase 1 Polyclonal Antibody – 1 ea

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Cayman
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SPHK 1 catalyzes the phosphorylation of sphingosine to sphingosine-1-phosphate. This reaction plays an important role in determining cell proliferation versus cell death.{13916,5545} SPHK 1 is found in a wide variety of tissues and cell types including kidney, liver, spleen, heart, platelets, and human tumors. On a cellular level, it is found in the cytosolic and membrane fractions.{14482} Based on the amino acid sequence, this protein has a molecular weight of approximately 43 kDa. The observed band at 50 kDa may be explained by some reported post translational modifications.{14483}  

 

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SKU: 10006822 - 1 ea Category:

Description

Antigen: human SPHK 1 amino acids 264-274 • Host: rabbit • Cross Reactivity: (+) human and mouse SPHK 1, expected to react with rat SPHK 1 • Application(s): ICC and WB • SPHK 1 catalyzes the phosphorylation of sphingosine to S1P. This reaction plays an important role in determining cell proliferation versus cell death.

Synonyms: SK 1|SPHK 1|SPK 1

Immunogen: Synthetic peptide from an internal region of human SPHK 1

Formulation: Lyophilized peptide affinity-purified antibody

Isotype:

Applications: ICC and WB; other applications not tested

Origin: Animal/Rabbit

Stability: 365 days

Application|Immunocytochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Lipid Biochemistry|Sphingolipids

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