Immunogen: Synthetic peptide from the C-terminal region of human SPT2 • Host: Rabbit • Species Reactivity: (+) Human

Serine Palmitoyltransferase Polyclonal Antibody – 1 ea

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Cayman
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Sphingolipids play essential roles in various cellular events, including proliferation, differentiation, senescence, apoptosis, and inflammatory responses.{12350} Serine palmitoyltransferase (SPT) is the initial and rate-limiting enzyme in the de novo sphingolipid biosynthesis, and thus regulates the level of sphingolipids in cells.{12348} Immunohistochemical study revealed widespread distribution of the enzyme with most strong expression in brain and digestive tract.{12347} Two subunits, SPT1 and SPT2 at a stoichiometry of 1:1, are involved in the enzymatic activity of SPT.{12349} Cayman Chemical’s SPT2 Polyclonal Antibody recognizes SPT2, the long chain subunit of the enzyme. The antibody stains mainly cell nuclei and occasionally both cell nuclei and cytoplasm in formalin-fixed, paraffin-embedded rat brain tissue. The nuclear localization of SPT2 may suggest that SPT2 associates with another nuclear protein or is modified and transported to the nucleus.{12348}  

 

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SKU: 10005260 - 1 ea Category:

Description

Immunogen: Synthetic peptide from the C-terminal region of human SPT2 • Host: Rabbit • Species Reactivity: (+) Human, bovine, mouse, ovine, porcine, rat, African green monkey SPT2 • Application(s): IHC and WB

Synonyms: Long Chain Biosynthesis Protein 2 (LCB2)|Serine-palmitoyl-CoA transferase 2 (SPT2)

Immunogen: Synthetic peptide from the C-terminal region of human SPT2

Formulation: Peptide affinity-purified IgG

Isotype:

Applications: IHC and WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area

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