Immunogen: Synthetic peptide from the C-terminal region of human 5-OxoETE receptor • Host: Rabbit • Species Reactivity: (+) Human

5-OxoETE Receptor Polyclonal Antibody – 500 µl

Brand:
Cayman
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5-Oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OxoETE) is a potent stimulator of chemotaxis for eosinophils and neutrophils that mediates its action via a putative G-protein coupled receptor (GPCR).{10476,11003} The 5-OxoETE receptor couples to Gi/o to inhibit cyclic AMP production and to mobilize intracellular calcium.{10476,11003} Northern blot analysis reveals that the receptor is highly expressed on eosinophils and neutrophils, suggesting a key role in the inflammatory response.{11003} In addition, the protein can also be detected in tissues such as kidney and liver.{10476,11003} Cayman Chemical’s 5-OxoETE Receptor Polyclonal Antibody can be used in Western blot analysis (detection at 48 kDa) and immunocytochemistry. The high expression level of the receptor in leukocytes makes it the best positive control sample. When probing other tissue samples such as liver and kidney, membrane preparations or higher sensitivity detection systems may be required for visualization on immunoblot.  

 

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SKU: 100025 - 500 µl Category:

Description

Immunogen: Synthetic peptide from the C-terminal region of human 5-OxoETE receptor • Host: Rabbit • Species Reactivity: (+) Human, Cos-7 (African green monkey), mouse, porcine, and rat • Applications: ICC and WB

Synonyms: GPR170|OXE Receptor|OXER1|Oxoeicosanoid Receptor 1|R527|TG1019

Immunogen: Synthetic peptide from the C-terminal region of human 5-OxoETE receptor

Formulation: 500 µl of Peptide affinity-purified antibody

Isotype:

Applications: ICC and WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Immunocytochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Cytochrome P450 Pathways

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