Cayman’s XTT Cell Proliferation Assay provides an easy to use tool for studying induction and inhibition of cell proliferation in any in vitro model. The assay is based on the extracellular reduction of XTT by NADH produced in the mitochondria via trans-plasma membrane electron transport and an electron mediator. Reduction of XTT produces a water-soluble formazan that dissolves directly into the culture medium

XTT Cell Proliferation Assay Kit – 480 wells

Brand:
Cayman
Storage:
-20

Defining the mechanisms responsible for alterations in cell cycle progression is crucial to understanding many human diseases, most notably cancer. Cell proliferation assays have been widely used to assess cell cycle regulatory factors such as growth factors, cytokines, mitogens, and drugs.{14191} Cayman’s XTT cell proliferation assay kit provides an easy to use tool for studying induction and inhibition of cell proliferation in any in vitro model. The assay is based on the extracellular reduction of XTT by NADH produced in the mitochondria via trans-plasma membrane electron transport and an electron mediator.{14422} Reduction of XTT produces a water-soluble formazan which dissolves directly into the culture medium, eliminating the need for an additional solubilization step. This kit will allow investigators to screen drug candidates involved in cell cycle regulation.  

 

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SKU: 10010200 - 480 wells Category:

Description

Cayman’s XTT Cell Proliferation Assay provides an easy to use tool for studying induction and inhibition of cell proliferation in any in vitro model. The assay is based on the extracellular reduction of XTT by NADH produced in the mitochondria via trans-plasma membrane electron transport and an electron mediator. Reduction of XTT produces a water-soluble formazan that dissolves directly into the culture medium, eliminating the need for an additional solubilization step. This kit will allow investigators to screen drug candidates involved in cell cycle regulation.

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Application|Cell-Based Assay||Product Type|Assay Kits|Cell-Based Assays||Research Area|Cell Biology|Cell Cycle||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Toxicology|Cell Health & Viability|Mitochondrial (dys)Function

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