Fluprostenol is a metabolically stable analog of PGF2α with potent FP receptor agonist activity. The isopropyl ester of fluprostenol has been approved for use as an ocular hypotensive drug for the treatment of glaucoma and is sold under the Alcon trade name Travoprost. Acting as a prodrug

Fluprostenol ELISA Kit – 96 solid wells

Brand:
Cayman
Storage:
-20

Fluprostenol is a metabolically stable analog of PGF2α with potent FP receptor agonist activity.{3160,1374} The isopropyl ester of fluprostenol has recently been approved for use as an ocular hypotensive drug for the treatment of glaucoma and is sold under the Alcon trade name Travoprost.{8839,9613} Acting as a prodrug, Fluprostenol isopropyl ester is converted by esterase activity in the cornea to yield the corresponding active free acid, (+)-fluprostenol.{1107} Fluprostenol is also used in the veterinary field for the induction of estrus in livestock. Cayman’s Fluprostenol ELISA is a sensitive detection method for measuring the free acid form of fluprostenol. The assay also detects the isopropyl ester form of fluprostenol, but with less sensitivity. Samples containing a mixture of the isopropyl ester and free acid should be purified and the compounds separated prior to analysis. The assay has been validated for use in aqueous humor samples.  

 

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SKU: 516761 - 96 solid wells Category:

Description

Fluprostenol is a metabolically stable analog of PGF2α with potent FP receptor agonist activity. The isopropyl ester of fluprostenol has been approved for use as an ocular hypotensive drug for the treatment of glaucoma and is sold under the Alcon trade name Travoprost. Acting as a prodrug, Fluprostenol isopropyl ester is converted by esterase activity in the cornea to yield the corresponding active free acid, (+)-fluprostenol. Cayman’s Fluprostenol ELISA is a sensitive detection method for measuring the free acid form of fluprostenol. The assay also detects the isopropyl ester form of fluprostenol, but with less sensitivity. The assay has been validated for use in aqueous humor samples.

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Synonyms:  16-m-trifluoromethylphenoxy tetranor Prostaglandin F2α EIA Kit

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Origin: Animal/Mouse|Animal/Bovine|Animal/Eel|Animal/Rabbit

Application|ELISA||Product Type|Assay Kits|ELISA||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology

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