α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase).{1199

α-hydroxy Farnesyl Phosphonic Acid – 1 mg

Brand:
Cayman
CAS:
148796-53-6
Storage:
-20
UN-No:
Non-Hazardous - /

α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase).{1199,5456} At concentrations greater than 1 µM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.{1196}  

 

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Description

α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase).{1199,5456} At concentrations greater than 1 µM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.{1196}

Formal name: (±)-1-hydroxy-3,7,11-trimethyl-2E,6E,10-dodecatriene-1-phosphonic acid

Synonyms:  Hydroxyfarnesyl Phosphate

Molecular weight: 302.4

CAS: 148796-53-6

Purity: ≥98%

Formulation: A crystalline solid

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