A quantitative analytical standard guaranteed to meet MaxSpec® identity

(±)5(6)-DiHET MaxSpec® Standard – 10 µg

Brand:
Cayman
CAS:
213382-49-1
Storage:
-20
UN-No:
De Minimis - 1170 / 3

5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET (Item Nos. 50211 | 10007260) by epoxide hydrolases.{729} 5(6)-DiHET can be used to quantify 5(6)-EET due to the conversion of 5(6)-EET to 5(6)-δ-lactone in solution.{39654} 5(6)-DiHET activates large conductance calcium-activated potassium (BK) channels in smooth muscle cells from rat small coronary arteries.{37444} It is a substrate for sheep seminal vesicle COX, producing 5,6-dihydroxy prostaglandin E1 and F1α metabolites in vitro.{461} 5(6)-DiHET levels decrease in plasma in a high-fat diet-induced rat model of hyperlipidemia.{37445} (±)5(6)-DiHET MaxSpec® standard is a quantitative grade standard of (±)5(6)-DiHET (Item No. 51211) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This (±)5(6)-DiHET MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.  

 

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SKU: 10007264 - 10 µg Category:

Description

A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications,

Formal name: (±)5,6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid

Synonyms:  (±)5,6-DiHETrE

Molecular weight: 338.5

CAS: 213382-49-1

Purity: ≥95%

Formulation: A solution in ethanol at 10 µg/ml

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards|MaxSpec®||Product Type|Biochemicals|Ion Channel Modulation|Activators||Product Type|Biochemicals|Lipids|Hydroxy/Hydroperoxy/ Epoxy/Oxo Eicosanoids||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Immunology & Inflammation||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Lipid Biochemistry|Cytochrome P450 Pathways

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