An epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo; its effects of remain to be determined

(±)11(12)-EpETE – 500 µg

Brand:
Cayman
CAS:
504435-15-8
Storage:
-20
UN-No:
Excepted Quantity - 1170 / 3

Eicosapentaenoic acid (EPA; Item No. 90110) is converted to epoxyeicosatetraenoic acids (EpETE) by several cytochrome P450 isoforms.{18671} The major product of this epoxygenase pathway, (±)17(18)-EpETE (Item No. 50861), relaxes vascular and airway smooth muscle by binding large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits.{9825,18669,18670} (±)11(12)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo.{18671,18672} The biological actions and physiological effects of this epoxide remain to be determined.  

 

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SKU: 10462 - 500 µg Category:

Description

An epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo; its effects of remain to be determined

Formal name: (±)11,12-epoxy-5Z,8Z,14Z,17Z- eicosatetraenoic acid

Synonyms:  (±)11,12-EEQ|(±)11,12-Epoxyeicosatetraenoic Acid

Molecular weight: 318.5

CAS: 504435-15-8

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Hydroxy/Hydroperoxy/ Epoxy/Oxo Eicosanoids||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Lipid Biochemistry|Cytochrome P450 Pathways

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