Description
A racemic mixture of (+)-WIN 55,212-2 and (−)-WIN 55,212-3; inhibits electrically induced contractions in mouse vas deferens preparations (IC50 = 0.006 µM) and reduces PG synthesis by 35% in mouse brain microsomes at 30 µM; decreases acetylcholine-induced writhing in mice (ED50 = 0.25 mg/kg); induces hypolocomotion, analgesia, hypothermia, and catalepsy in mice (ED50s = 1.09, 0.5, 3.01 and 6.8 mg/kg, respectively)
Formal name: [2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanone, methanesulfonate
Synonyms:
Molecular weight: 522.6
CAS: 137795-17-6
Purity: ≥98%
Formulation: A crystalline solid
Application||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors||Research Area|Neuroscience|Pain Research