A non-selective COX inhibitor (IC50s = 0.5 and 2.33 µM for human COX-1 and COX-2

(±)-Ketoprofen – 5 g

Brand:
Cayman
CAS:
22071-15-4
Storage:
-20
UN-No:
Excepted Quantity - 2811 / 6.1

(±)-Ketoprofen is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID).{1286} It inhibits human recombinant COX-1 and COX-2 with IC50 values of 0.5 and 2.33 µM, respectively. In vivo, (±)-ketoprofen reduces carrageenan-induced paw edema and increases latency to paw withdrawal in the hot plate test in rats when administered using a sustained-release implant.{42815} Formulations containing (±)-ketoprofen have been used to treat pain and inflammation in osteoarthritis.  

 

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SKU: 10006661 - 5 g Category:

Description

A non-selective COX inhibitor (IC50s = 0.5 and 2.33 µM for human COX-1 and COX-2, respectively); reduces carrageenan-induced paw edema and increases latency to paw withdrawal in the hot plate test in rats when administered using a sustained-release implant,

Formal name: 3-benzoyl-α-methyl-benzeneacetic acid

Synonyms:  (R,S)-Ketoprofen|2-(3-benzoylphenyl)Propionic Acid

Molecular weight: 254.3

CAS: 22071-15-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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