A metabolite of propranolol and 4-hydroxy propranolol; has an apparent half-life similar to propranolol and 4-hydroxy propranolol

(±)-4-hydroxy Propranolol β-D-Glucuronide – 1 mg

Brand:
Cayman
CAS:
94731-13-2
Storage:
-20
UN-No:
Non-Hazardous - /

(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol (Item No. 18630), which is a metabolite of propranolol.{36036,36037} The apparent half-life of (±)-4-hydroxy propranolol β-D-glucuronide is similar to propranolol and 4-hydroxy propranolol.{36037} Propranolol is a β-adrenergic antagonist, and the active enantiomer, (S)-(-)-propranolol (Item No. 17291), has log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively.{25151,25396}  

 

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Description

A metabolite of propranolol and 4-hydroxy propranolol; has an apparent half-life similar to propranolol and 4-hydroxy propranolol,

Formal name: 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-1-naphthalenyl β-D-glucopyranosiduronic acid

Synonyms: 

Molecular weight: 451.5

CAS: 94731-13-2

Purity: ≥90%

Formulation: A solid

Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Cardiovascular Diseases|Angina||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Cardiovascular Diseases|Myocardial Infarction||Research Area|Cardiovascular System|Heart|Arrhythmia||Research Area|Cardiovascular System|Heart|Myocardial Contractility||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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