A triptan that acts as an agonist of the serotonin (5-HT) receptors 5-HT1B and 5-HT1D (Kis = 2.2 and 0.92 nM

Zolmitriptan – 5 mg

Brand:
Cayman
CAS:
139264-17-8
Storage:
-20
UN-No:
Non-Hazardous - /

Zolmitriptan is a triptan that acts as an agonist of the serotonin (5-HT; Item No. 14332) receptors 5-HT1B and 5-HT1D (Kis = 2.2 and 0.92 nM, respectively).{25800,25801} Through this action, zolmitriptan inhibits cAMP formation in blood vessels, resulting in vessel constriction.{25800,25801} Triptans, including zolmitriptan, are considered first-line therapy for moderate to severe migraine.{25802}  

 

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Description

A triptan that acts as an agonist of the serotonin (5-HT) receptors 5-HT1B and 5-HT1D (Kis = 2.2 and 0.92 nM, respectively); inhibits cAMP formation in blood vessels, resulting in vessel constriction

Formal name: 4S-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone

Synonyms:  BW 311C90|Zomig®

Molecular weight: 287.4

CAS: 139264-17-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Pain Research

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