A nucleoside reverse transcriptase inhibitor that

Zidovudine – 1 g

Brand:
Cayman
CAS:
30516-87-1
Storage:
-20
UN-No:
Non-Hazardous - /

Zidovudine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC50 = 3 nM) with low cytotoxicity (CC50 > 5 μM).{25338,25340,25341,25339} It is commonly used in combination therapy to slow the replication of HIV in vivo.{25337}  

 

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Description

A nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC50 = 3 nM) with low cytotoxicity (CC50 > 5 μM)

Formal name: 3’-azido-3’-deoxy-thymidine

Synonyms:  Azidothymidine|AZT|NSC 602670|Retrovir|ZDV

Molecular weight: 267.3

CAS: 30516-87-1

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals|Nucleoside Reverse Transcriptase Inhibitors (NRTIs)||Product Type|Biochemicals|Nucleotides/Nucleosides||Product Type|Biochemicals|Small Molecule Inhibitors|Reverse Transcriptases||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS

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