A natural monocyclic sesquiterpene that potently inhibits the activation of Epstein-Barr virus by phorbol esters (IC50 = 140 nM); inhibits SHH signaling and induces apoptosis in cancer cell lines

Zerumbone – 5 mg

Brand:
Cayman
CAS:
471-05-6
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet.{24909} It potently inhibits the activation of Epstein-Barr virus by phorbol esters (IC50 = 140 nM).{24909,24908} Zerumbone inhibits Sonic hedgehog signaling and induces apoptosis in cancer cell lines.{22122,24911,24910} It has also been shown to have anti-oxidant and anti-inflammatory activities, contributing to immunomodulatory and hepatoprotective effects.{24912}  

 

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Description

A natural monocyclic sesquiterpene that potently inhibits the activation of Epstein-Barr virus by phorbol esters (IC50 = 140 nM); inhibits SHH signaling and induces apoptosis in cancer cell lines

Formal name: (2E,6E)-2,6,9,9-tetramethyl-2,6,10E-cycloundecatrien-1-one

Synonyms: 

Molecular weight: 218.3

CAS: 471-05-6

Purity: ≥99%

Formulation: Solid white crystals or powder

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|Hedgehog Signaling||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|Epstein-Barr||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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