Description
A carotenoid with hepatoprotective activity; inhibits TGF-β-induced activation of hepatic stellate cells (IC50 = 186.34 µM); reduces hepatic collagen deposition and TBARS levels, as well as serum AST and ALP activity, in a rat model of bile duct ligation-induced hepatic fibrosis at 25 mg/kg; reduces hepatic steatosis, inflammation, and fibrosis in a model of NASH induced by a methionine choline-deficient diet in HBV transgenic mice
Formal name: (3R,3′R)-β,β-carotene-3,3′-diol, 3,3′-dihexadecanoate
Synonyms: Physalien
Molecular weight: 1,045.70
CAS: 144-67-2
Purity: ≥95%
Formulation: A crystalline solid
