An NSAID that displays slight preferential inhibition for COX-2 (IC50s = 1.3 and 0.34 μM for COX-1 and COX-2

Zaltoprofen – 250 mg

Brand:
Cayman
CAS:
74711-43-6
Storage:
-20
UN-No:
Non-Hazardous - /

Zaltoprofen is a cyclooxygenase (COX) inhibitor that displays slight preferential inhibition for COX-2 (IC50s = 1.3 and 0.34 μM for COX-1 and COX-2, respectively).{23288} Independent of COX inhibition, zaltoprofen has also been reported to inhibit bradykinin-induced nociceptive responses by blocking the activation of protein kinase C.{23287}  

 

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Description

An NSAID that displays slight preferential inhibition for COX-2 (IC50s = 1.3 and 0.34 μM for COX-1 and COX-2, respectively); also inhibits bradykinin-induced nociceptive responses by blocking the activation of PKC

Formal name: 10,11-dihydro-a-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid

Synonyms:  CN 100|Soleton

Molecular weight: 298.4

CAS: 74711-43-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|PKC||Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Leukotrienes||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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