A fluorogenic substrate for the chymotrypsin-like activity of the 26S proteasome or 20S proteolytic core

Z-LLL-AMC – 5 mg

Brand:
Cayman
CAS:
152015-61-7
Storage:
-20
UN-No:
Non-Hazardous - /

Z-LLL-AMC is a fluorogenic substrate for the chymotrypsin-like activity of the 26S proteasome or 20S proteolytic core.{32464,32465,32463} Chymotrypsin-like activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Z-LLL-AMC is typically used in cell lysates after experimental treatment.{32462}  

 

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SKU: 10008118 - 5 mg Category:

Description

A fluorogenic substrate for the chymotrypsin-like activity of the 26S proteasome or 20S proteolytic core

Formal name: N-[(phenylmethoxy)carbonyl]-L-leucyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-leucinamide

Synonyms:  Proteasome Substrate I|Z-Leu-Leu-Leu-7-amido-4-Methylcoumarin|Z-Leu-Leu-Leu-AMC

Molecular weight: 648.8

CAS: 152015-61-7

Purity: ≥98%

Formulation: A solid

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Proteolysis|Ubiquitin/Proteasome System

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