A cell-permeable irreversible inhibitor of caspase-3 (IC50 = 130 nM); potently inhibits apoptosis

Z-DEVD-FMK – 5 mg

Brand:
Cayman
CAS:
210344-95-9
Storage:
-20
UN-No:
Non-Hazardous - /

Caspase-3 is a cysteinyl aspartate-specific protease which plays a central role in apoptosis.{22735} Z-DEVD-FMK is a cell-permeable irreversible inhibitor of caspase-3 (IC50 = 130 nM).{22734,22737} It potently inhibits apoptosis.{22736}  

 

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Description

A cell-permeable irreversible inhibitor of caspase-3 (IC50 = 130 nM); potently inhibits apoptosis

Formal name: N-[(phenylmethoxy)carbonyl]-L-α-aspartyl-L-α-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-valinamide, 1,2-dimethyl ester

Synonyms: 

Molecular weight: 668.7

CAS: 210344-95-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Small Molecule Inhibitors|Caspases||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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