A fluorogenic substrate for caspase-3; AFC is released upon cleavage by caspase-3 and its fluorescence can be used to quantify caspase-3 activity

Z-DEVD-AFC – 1 mg

Brand:
Cayman
CAS:
1135416-11-3
Storage:
-20
UN-No:
Non-Hazardous - /

Z-DEVD-AFC is a fluorogenic substrate for caspase-3.{36443} Upon cleavage by caspase-3, 7-amino-7-trifluoromethylcoumarin (AFC) is released and its fluorescence can be used to quantify caspase-3 activity. AFC displays excitation/emission maxima of 400/505 nm, respectively.  

 

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SKU: 24564 - 1 mg Category:

Description

A fluorogenic substrate for caspase-3; AFC is released upon cleavage by caspase-3 and its fluorescence can be used to quantify caspase-3 activity

Formal name: (5S,8S,11S,14S)-8-(2-carboxyethyl)-5-(carboxymethyl)-11-isopropyl-3,6,9,12-tetraoxo-14-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oic acid

Synonyms:  Caspase-3 Fluorogenic Substrate IV

Molecular weight: 821.7

CAS: 1135416-11-3

Purity: ≥95%

Formulation: A lyophilized powder

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases||Research Area|Neuroscience

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