A prodrug form of YH 239; inhibits the growth of OCI-AML-3 cells and halts the cell cycle at the sub-G1 phase and induces apoptosis in NB4 and MOLM-13 cells at 20 μM

YH 239-EE – 50 mg

Brand:
Cayman
CAS:
1364488-67-4
Storage:
-20
UN-No:
Non-Hazardous - /

YH 239-EE is an ethyl ester prodrug form of YH 239, a potent inhibitor of the p53-MDM2 protein-protein interaction.{52286} YH 239-EE (20 μM) inhibits the growth of OCI-AML-3 cells and halts the cell cycle at the sub-G1 phase and induces apoptosis in NB4 and MOLM-13 cells.  

 

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SKU: 27678 - 50 mg Category:

Description

A prodrug form of YH 239; inhibits the growth of OCI-AML-3 cells and halts the cell cycle at the sub-G1 phase and induces apoptosis in NB4 and MOLM-13 cells at 20 μM

Formal name: 6-chloro-3-[1-[[(4-chlorophenyl)methyl]formylamino]-2-[(1,1-dimethylethyl)amino]-2-oxoethyl]-1H-indole-2-carboxylic acid, ethyl ester

Synonyms: 

Molecular weight: 504.4

CAS: 1364488-67-4

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals||Research Area|Cancer|Cell Cycle||Research Area|Cancer|Cell Death|Apoptosis

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