Inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397; decreases cell viability of T47D breast cancer and C8161 melanoma cell lines at 100 µM

Y11 – 25 mg

Brand:
Cayman
CAS:
1086639-59-9
Storage:
-20
UN-No:
Non-Hazardous - /

Focal adhesion kinases (FAKs) are non-receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are over-expressed in many types of cancer. Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397.{23133} At 100 µM, it was shown to decrease cell viability of T47D breast cancer and C8161 melanoma cell lines.{23133}  

 

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Description

Inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397; decreases cell viability of T47D breast cancer and C8161 melanoma cell lines at 100 µM

Formal name: 1-(2-hydroxyethyl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane, monobromide

Synonyms:  FAK Inhibitor 10|NSC 206142

Molecular weight: 265.2

CAS: 1086639-59-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|Other Non-Receptor Tyrosine Kinases||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling

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