A coumarin; active against R. solani

Xanthyletin – 5 mg

Brand:
Cayman
CAS:
553-19-5
Storage:
-20
UN-No:
Non-Hazardous - /

Xanthyletin is a coumarin that has been found in Z. avicennae and has diverse biological activities, including antifungal, antioxidant, and anticancer properties.{52299,52300,52301} It is active against the fungi R. solani, F. graminearum, and P. oryzae (IC50s = 49.1, 117.2, and 31.6 mg/L, respectively).{52299} Xanthyletin (50 mg/L) is also active against F. oxysporum, A. solani, and S. sclerotiorum. It reduces LPS-induced production of nitric oxide (NO) in BV-2 microglial cells with an IC50 value of 5.4 µM.{52300} Xanthyletin inhibits proliferation of A549 lung, MCF-7 breast, and PC3 prostate cancer cells (IC50s = 80.1, 19.3, and 97.2 µg/ml, respectively).{52301}  

 

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SKU: 29929 - 5 mg Category:

Description

A coumarin; active against R. solani, F. graminearum, and P. oryzae (IC50s = 49.1, 117.2, and 31.6 mg/L, respectively); active against F. oxysporum, A. solani, and S. sclerotiorum at 50 mg/L; reduces LPS-induced production of NO in BV-2 microglial cells (IC50 = 5.4 µM); inhibits proliferation of A549 lung, MCF-7 breast, and PC3 prostate cancer cells (IC50s = 80.1, 19.3, and 97.2 µg/ml, respectively)

Formal name: 8,8-dimethyl-2H,8H-Benzo[1,2-b:5,4-b′]dipyran-2-one

Synonyms:  2,2-Dimethylchromenocoumarin

Molecular weight: 228.2

CAS: 553-19-5

Purity: ≥95%

Formulation: A solid

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