An endogenous mGluR2 and mGluR3 agonist implicated in the pathophysiology of schizophrenia; induces gametogenesis of P. falciparum

Xanthurenic Acid – 1 g

Brand:
Cayman
CAS:
59-00-7
Storage:
-20
UN-No:
Non-Hazardous - /

Xanthurenic acid is formed upon tryptophan degradation by indoleamine 2,3-dioxygenase. It has been shown to be an endogenous Group II metabotropic glutamate receptor (mGluR2 and mGluR3) agonist and is implicated in the pathophysiology of schizophrenia.{31730,31731} Xanthurenic acid has also been identified as an inducer of gametogenesis of P. falciparum, the parasite that causes malaria, and thus, is a target for the development of new methods to interrupt the transmission of malaria.{6156}  

 

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Description

An endogenous mGluR2 and mGluR3 agonist implicated in the pathophysiology of schizophrenia; induces gametogenesis of P. falciparum

Formal name: 4,8-dihydroxy-2-quinolinecarboxylic acid

Synonyms:  NSC 401570|Xanthurenate

Molecular weight: 205.2

CAS: 59-00-7

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases|Malaria||Research Area|Neuroscience|Behavioral Neuroscience|Schizophrenia & Psychosis

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