An antibiotic that suppresses the expression of ODC

Xanthorrhizol – 1 mg

Brand:
Cayman
CAS:
30199-26-9
Storage:
-20
UN-No:
Non-Hazardous - /

Xanthorrhizol is a sesquiterpenoid isolated from the rhizome of C. xanthorrhiza that exhibits antibacterial and antifungal activity, neuroprotective activity, and protective effects against chemotherapeutic drug-induced hepatotoxicity and nephrotoxicity.{23323} Xanthorrhizol suppresses the expression of ornithine decarboxylase, cyclooxygenase-2, and inducible nitric oxide synthase at concentrations as low as 0.3 μM.{23322,23321} It exhibits an anti-metastasis effect and anti-tumor promoter activity in various mouse models of carcinogenesis.{23322,23321} Xanthorrhizol inhibits the proliferation of human colon cancer HCT116 cells with an IC50 value of 54.8 μM by inducing cell cycle arrest and apoptosis.{23323}  

 

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Description

An antibiotic that suppresses the expression of ODC, COX-2, and iNOS at concentrations as low as 0.3 μM and exhibits an anti-metastasis effect and anti-tumor promoter activity in various carcinogenesis mouse models

Formal name: 5-[(1R)-1,5-dimethyl-4-hexen-1-yl]-2-methyl-phenol

Synonyms: 

Molecular weight: 218.3

CAS: 30199-26-9

Purity: ≥97%

Formulation: An oil

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Natural Products|Terpenes||Research Area|Cancer|Cell Cycle||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Fungal Diseases

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