A potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3

Xanomeline (oxalate) – 1 mg

Brand:
Cayman
CAS:
141064-23-5
Storage:
-20
UN-No:
Non-Hazardous - /

Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Xanomeline (oxalate) is a potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively).{19164} It has antipsychotic-like activities in rats and Cebus monkeys.{19522,19524} M1 selective agonists, like Xanomeline (oxalate), enhance memory function and has utility in treating Alzheimer’s Disease.{19523}  

 

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SKU: 10790 - 1 mg Category:

Description

A potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively); has antipsychotic-like activities in rats and Cebus monkeys; enhances memory function and has utility in treating Alzheimer’s Disease

Formal name: 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-pyridine, ethanedioate

Synonyms:  Lumeron|LY246708|Memcor

Molecular weight: 371.5

CAS: 141064-23-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Neuroscience|Behavioral Neuroscience|Schizophrenia & Psychosis||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease

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