WYE-28 – 1 mg

Brand:
Cayman
CAS:
1062172-60-4
Storage:
-20
UN-No:
Non-Hazardous - /

WYE-23 is an inhibitor of mammalian target of rapamycin (mTOR; IC50 = 0.08 nM).{20314,48484} It is selective for mTOR over PI3Kα (IC50 = 6 nM).{20314} WYE-23 inhibits cell growth in LNCaP cells (IC50 = <1 nM).  

 

Out of stock

SKU: 21200 - Category:

Description

An inhibitor of mTOR (IC50 = 0.08 nM); selective for mTOR over PI3Kα (IC50 = 6 nM); inhibits cell growth in LNCaP cells (IC50 = <1 nM)


Formal name: 4-[6-[4-[[[[4-(hydroxymethyl)phenyl]amino]carbonyl]amino]phenyl]-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinecarboxylic acid, methyl ester

Synonyms: 

Molecular weight: 586.6

CAS: 1062172-60-4

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Kinase Inhibitors|mTOR||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|PI3K/Akt/mTOR Signaling