(+)-Warfarin – 1 mg

Brand:
Cayman
CAS:
5543-58-8
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

(+)-Warfarin is a component of (±)-warfarin (Item No. 13566). It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting.{17423} In vivo, (+)-warfarin slows formation of the prothrombin complex but exhibits 6.6-fold less potent anticoagulant activity than (–)-warfarin (Item No. 13531) in rats.{36879} Formulations containing warfarin have been used to treat and prevent blood clots in atrial fibrillation, heart valve replacement, venous thrombosis, and pulmonary embolism.  

 

SKU: - Category:

Description

An anticoagulant; interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting; slows formation of the prothrombin complex but exhibits 6.6-fold less potent anticoagulant activity than (–)-warfarin in rats,


Formal name: 4-hydroxy-3-[(1R)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one

Synonyms:  (R)-Warfarin

Molecular weight: 308.3

CAS: 5543-58-8

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Small Molecule Inhibitors|Blood Coagulation Factors||Research Area|Cardiovascular System|Blood|Acute Phase Reactants||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Blood|Thrombosis||Research Area|Cardiovascular System|Heart|Arrhythmia