Description
A selective agonist of M1 mAChRs (Ki = 9.91 µM); selective for M1 over M2-M5 mAChRs (Kis = 21.4-50 µM in CHO cells); increases calcium mobilization and activates the ERK signaling pathway (EC50 = 1.6 and 37 µM, respectively, in CHO cells expressing human recombinant M1 receptors); reverses scopolamine-induced deficits in contextual fear conditioning in rats (10 mg/kg)
Formal name: 4-[[2-[(2-methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid, ethyl ester, monohydrochloride
Synonyms: CID-25010775
Molecular weight: 369.9
CAS: 1135242-13-5
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory
