A partial antagonist of mGluR5; inhibits calcium mobilization induced by glutamate in HEK293 cell membranes expressing rat mGluR5 (IC50 = 1.7 µM)

VU0029251 – 1 mg

Brand:
Cayman
CAS:
330819-85-7
Storage:
-20
UN-No:
Non-Hazardous - /

VU0029251 is a partial antagonist of metabotropic glutamate receptor 5 (mGluR5; Ki = 1.07 µM).{47575} It inhibits calcium mobilization induced by glutamate in HEK293 cell membranes expressing rat mGluR5 (IC50 = 1.7 µM).  

 

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Description

A partial antagonist of mGluR5; inhibits calcium mobilization induced by glutamate in HEK293 cell membranes expressing rat mGluR5 (IC50 = 1.7 µM)

Formal name: 6,7-dihydro-2-(methylthio)-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine

Synonyms: 

Molecular weight: 237.3

CAS: 330819-85-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Allosteric Modulators||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience

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