An internal standard for the quantification of vitamin D3 by GC- or LC-MS

Vitamin D3-d7 – 500 µg

Brand:
Cayman
CAS:
1627523-19-6
Storage:
-80
UN-No:
De Minimis - 2811 / 6.1

Vitamin D3-d7 is intended for use as an internal standard for the quantification of vitamin D3 (Item No. 11792) by GC- or LC-MS. Vitamin D3 is a biologically inactive precursor to calcitriol (Item No. 71820) that is converted to active metabolites in vivo.{23284,15096} Vitamin D3 is obtained from dietary sources, including fish, or formed in the epidermis via photolytic conversion of 7-dehydro cholesterol (Item No. 14612) to previtamin D3 by UVB radiation, followed by isomerization to vitamin D3.{19039,23286} Vitamin D3 can then be converted to 25-hydroxy vitamin D3 (Item No. 9000683) in the liver by the cytochrome P450 (CYP) isoform CYP2R1 before being converted to calcitriol by CYP27B1 in the kidney.{15096,19039} Formulations containing vitamin D3 have been used in the treatment of osteoporosis.  

 

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SKU: 25427 - 500 µg Category:

Description

An internal standard for the quantification of vitamin D3 by GC- or LC-MS

Formal name: (1S,3Z)-4-methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-7a-methyl-1-[(1R)-1-methyl-5-(methyl-d3)hexyl-5,6,6,6-d4]-4H-inden-4-ylidene]ethylidene]-cyclohexanol

Synonyms:  Cholecalciferol-d7

Molecular weight: 391.7

CAS: 1627523-19-6

Purity: ≥99% deuterated forms (d1-d7)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Natural Products|Vitamins||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling||Research Area|Endocrinology & Metabolism|Cofactors & Vitamins||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Vitamin D Receptor

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