A macrolide antibiotic; acts synergistically with virginiamycin M1 to irreversibly inhibit protein synthesis in bacteria

Virginiamycin S1 – 5 mg

Brand:
Cayman
CAS:
23152-29-6
Storage:
-20
UN-No:
Non-Hazardous - /

Virginiamycin S1 is a macrolide antibiotic that is a component of the virginiamycin complex (Item No. 14503), which also contains virginiamycin M1 (Item No. 9002172).{39373} It is a member of the streptogramin B group of antibiotics, which bind the 50S ribosomal subunit at the peptidyl transferase center to inhibit initiation and translocation.{27765} They show good bactericidal activity against methicillin-resistant S. aureus (MRSA), although resistance in MRSA is conferred by the cfr gene.{27765,28231} Virginiamycin S1 acts synergistically with virginiamycin M1 to irreversibly inhibit protein synthesis in bacteria.{23008}  

 

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Description

A macrolide antibiotic; acts synergistically with virginiamycin M1 to irreversibly inhibit protein synthesis in bacteria,

Formal name: N-((6R,9S,10R,13S,15aS,22S,24aS)-22-benzyl-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyldocosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1]oxa[4,7,10,13,16]pentaazacyclononadecin-9-yl)-3-hydroxypicolinamide

Synonyms:  Antibiotic 1754Z3B|Staphylomycin S1

Molecular weight: 823.9

CAS: 23152-29-6

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics|Macrolides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA

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