Description
A selectve adenosine A2A receptor antagonist (Kis = 1.3, 68, 63, and 1,005 nM for A2A, A1, A2B, and A3 receptors, respectively in a radio ligand binding assay); acts as a functional antagonist of human recombinant A2A (KA = 0.58 nM) in a calcium mobilization-based FLIPR assay; reverses haloperidol-induced hypolocomotion in mice and rats,
Formal name: 3-[(4-amino-3-methylphenyl)methyl]-7-(2-furanyl)-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine
Synonyms: BIIB-014
Molecular weight: 321.3
CAS: 442908-10-3
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease
