A metabolite of vinclozolin

Vinclozolin M2 – 50 mg

Brand:
Cayman
CAS:
83792-61-4
Storage:
-20
UN-No:
Non-Hazardous - /

Vinclozolin is a dicarboximide fungicide widely used in Europe and the United States for control of diseases caused by B. cinerea, S. sclerotiorum, and Monilinia species in grapes, fruits, vegetables, ornamental plants, and turfgrass.{13372} Metabolites of vinclozolin, M1 and M2, are effective antagonists of the androgen receptor in rats exhibiting Ki values of 92 and 9.7 µM respectively.{13216} In fathead minnow, M1 and M2 failed to compete for high-affinity, low capacity testosterone binding sites in brain and ovary cytosolic fractions suggesting that they are not anti-androgens in this species.{13374}  

 

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SKU: 10007452 - 50 mg Category:

Description

A metabolite of vinclozolin, a dicarboximide fungicide, that acts as an effective antagonist of the androgen receptor (Ki = 9.7 µM in rat)

Formal name: N-(3,5-dichlorophenyl)-2-hydroxy-2-methyl-3-butenamide

Synonyms:  M2

Molecular weight: 260.1

CAS: 83792-61-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Pesticides|Fungicides||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Endocrinology & Metabolism

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