A major metabolite of vildagliptin; IC50 = 477 µM for DPP-4 in human Caco-2 cells; formed from hydrolysis of the cyano group on vildagliptin

Vildagliptin carboxylic acid metabolite (trifluoroacetate salt) – 5 mg

Brand:
Cayman
CAS:
565453-41-0
Storage:
-20
UN-No:
Non-Hazardous - /

Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin (Item No. 14705) in humans.{41126} Vildagliptin carboxylic acid metabolite has an IC50 value of 477 µM for DPP-4 in human Caco-2 cells.{41127} It is formed from hydrolysis of the cyano group on vildagliptin.  

 

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Description

A major metabolite of vildagliptin; IC50 = 477 µM for DPP-4 in human Caco-2 cells; formed from hydrolysis of the cyano group on vildagliptin

Formal name: N-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-proline, mono(trifluoroacetate)

Synonyms: 

Molecular weight: 436.4

CAS: 565453-41-0

Purity:

Formulation: A solid

Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Immunology & Inflammation||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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