A natural compound with strong antioxidant activity; potently inhibits the release of TNF-α (IC50 = 0.09 nM) and IL-4 (IC50 = 2.8 nM)

Vialinin A – 1 mg

Brand:
Cayman
CAS:
858134-23-3
Storage:
-20
UN-No:
Non-Hazardous - /

Vialinin A is a terphenyl compound originally isolated from the fungi T. terrestris and T. vialis.{15824,15825} Terphenyls, in general, are recognized as strong antioxidants.{15826} Vialinin A potently inhibits the release of TNF-α (IC50 = 0.09 nM) and IL-4 (IC50 = 2.8 nM), as well as β-hexosaminidase and CCL2 (MCP-1) from IgE-stimulated RBL-2H3 mast cells.{15827} Vialinin A does not significantly increase lactate dehydrogenase release from RBL-2H3 mast cells, suggesting low cytotoxicity.{15827}  

 

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SKU: 10010519 - 1 mg Category:

Description

A natural compound with strong antioxidant activity; potently inhibits the release of TNF-α (IC50 = 0.09 nM) and IL-4 (IC50 = 2.8 nM), as well as β-hexosaminidase and CCL2 (MCP-1) from IgE-stimulated RBL-2H3 mast cells

Formal name: 4,4”,5’,6’-tetrahydroxy[1,1’:4’,1”-terphenyl]-2’,3’-diyl ester benzeneacetic acid

Synonyms:  Terrestrin A

Molecular weight: 562.6

CAS: 858134-23-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Immunology & Inflammation|Innate Immunity

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