An antifungal agent that inhibits trehalase

Validamycin A – 100 mg

Brand:
Cayman
CAS:
37248-47-8
Storage:
-20
UN-No:
Non-Hazardous - /

Validamycin A is an antifungal agent used to protect rice plants against sheath blight caused by the pathogenic fungus, R. solani, due to its ability to inhibit trehalase, a trehalose-hydrolizing enzyme (Ki = 1.9 nM; IC50 = 0.7 μM).{24963} It is also effective against the growth and sporulation of R. cerealis, F. culmorum, and other fungi.{24962} This compound has also been used to study trehalase activity and trehalose biosynthesis.{24961}  

 

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Description

An antifungal agent that inhibits trehalase, a trehalose-hydrolizing enzyme (Ki = 1.9 nM; IC50 = 0.7 μM); used to protect rice plants against sheath blight caused by the pathogenic fungus, R. solani and also effective against the growth and sporulation of R. cerealis, F. culmorum, and other fungi

Formal name: 1,5,6-trideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-D-chiro-inositol

Synonyms:  Validacin

Molecular weight: 497.5

CAS: 37248-47-8

Purity: ≥60%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Pesticides|Fungicides||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Plant Biology|Phytoprotectants

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